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Understanding ENERGY METABOLISM IN HEALTH AND DISEASE
Understanding ENERGY METABOLISM IN HEALTH AND DISEASE
Scientists identified a protein that triggers changes in mitochondria that lead to reduced fat-burning to promote weight gain in mice fed a high-fat diet.
The findings may point to potential new avenues for treating or preventing obesity in people.
UC San Diego study reveals key mechanism behind obesity-related metabolic dysfunction
After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, researchers were able to use these pathways to halt further liver damage.
In the News...
Eureka Alert – July 5th, 2018
Repurposed asthma drug shows blood sugar improvement among some diabetics
After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.
In the News
Science Daily – February 8th 2018
Enzyme plays a key role in calories burned both during obesity and dieting
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a new paper, researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
More In the News...
Fierce Biotech – February 8th 2018
Fighting obesity by controlling inflammation
The San Diego Union Tribune - September 22nd 2016
How to battle cancer linked to obesity
Science - October 10, 2014
New class of fatty molecules battles diabetes in mice
USA Today - July 1, 2013
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